Last Updated: February 2026 | Reviewed by Dr. Davinder Sidhu, OD
Tobradex Eye Drops in Canada: Uses, Side Effects & Alternatives
Tobradex is a widely prescribed combination eye drop used to treat bacterial eye infections accompanied by inflammation. Available by prescription in Canada, it combines two active ingredients: tobramycin (an antibiotic) and dexamethasone (a corticosteroid). Together, they fight infection while reducing swelling, redness, and discomfort.
In this guide, we'll cover everything you need to know about Tobradex eye drops, including how they work, proper usage, potential side effects, and available alternatives in Canada.
What Is Tobradex?
Tobradex is a prescription ophthalmic suspension manufactured by Novartis (now Alcon). It contains:
- Tobramycin 0.3%: An aminoglycoside antibiotic that kills bacteria by inhibiting protein synthesis.
- Dexamethasone 0.1%: A corticosteroid that reduces inflammation, swelling, redness, and itching.
This combination makes Tobradex effective for conditions where both infection and inflammation are present.
Uses for Tobradex Eye Drops
Tobradex is commonly prescribed for:
- Bacterial conjunctivitis (pink eye): When bacterial infection is accompanied by significant inflammation.
- Post-surgical eye care: After cataract surgery or other eye procedures to prevent infection and control inflammation.
- Blepharitis: Inflammation of the eyelids caused by bacterial infection.
- Corneal injuries: When there's a risk of bacterial infection with inflammation.
- Other bacterial eye infections: Where both antibiotic and anti-inflammatory treatment is needed.
How Tobradex Works
The two active ingredients in Tobradex work together:
Tobramycin targets and kills susceptible bacteria by binding to the 30S ribosomal subunit, preventing the bacteria from producing essential proteins needed for growth and survival.
Dexamethasone reduces the body's inflammatory response by suppressing the migration of white blood cells and reducing capillary permeability. This helps alleviate symptoms like redness, swelling, and pain.
How to Use Tobradex Eye Drops
Follow your doctor's instructions carefully. General guidelines include:
- Wash your hands thoroughly before use.
- Shake the bottle well before each use.
- Tilt your head back and pull down your lower eyelid to create a small pocket.
- Hold the dropper above your eye and squeeze one drop into the pocket.
- Close your eye gently and press on the inner corner (near your nose) for 1 to 2 minutes to prevent the drops from draining.
- Wait at least 5 minutes between applying different eye medications.
- Do not touch the dropper tip to any surface to avoid contamination.
Typical dosage is one or two drops in the affected eye(s) every 4 to 6 hours. Your doctor may adjust this based on the severity of your condition.
Side Effects of Tobradex
Like all medications, Tobradex can cause side effects. Common side effects include:
- Temporary stinging or burning upon application
- Blurred vision (temporary)
- Eye irritation or redness
- Unusual taste in the mouth
Less common but more serious side effects may include:
- Increased intraocular pressure (IOP): Prolonged use of corticosteroids like dexamethasone can raise eye pressure, potentially leading to glaucoma.
- Delayed wound healing: Steroids can slow the healing process.
- Secondary infections: Prolonged antibiotic use can lead to fungal overgrowth or resistant bacterial strains.
- Cataract formation: Long-term steroid use around the eyes can increase cataract risk.
Contact your eye care professional immediately if you experience severe eye pain, vision changes, or signs of a new infection.
Precautions and Warnings
- Do not use Tobradex if you have a viral or fungal eye infection (e.g., herpes simplex keratitis).
- Inform your doctor if you have glaucoma or a history of elevated eye pressure.
- Do not wear contact lenses while using Tobradex unless directed by your doctor.
- Do not use for longer than prescribed. Prolonged steroid use increases the risk of serious side effects.
- Tell your doctor about all other medications you are taking.
Allergic Reactions
Although rare, some people may experience allergic reactions to Tobradex. Symptoms may include:
- Severe eye swelling or itching
- Rash or hives
- Difficulty breathing
- Swelling of the face, lips, tongue, or throat
If you experience any signs of an allergic reaction, stop using Tobradex immediately and seek emergency medical attention.
Alternatives to Tobradex in Canada
If Tobradex isn't suitable for you, your doctor may recommend alternatives:
- Tobradex ST: A newer formulation with a lower concentration of dexamethasone (0.05%) that may cause fewer steroid-related side effects.
- Maxitrol: Contains neomycin, polymyxin B, and dexamethasone. Another combination antibiotic-steroid option.
- Zymar/Zymaxid (gatifloxacin): A fluoroquinolone antibiotic without a steroid component, for cases where inflammation is not a major concern.
- Vigamox (moxifloxacin): Another fluoroquinolone antibiotic eye drop.
For general dry eye relief and comfort between treatments, preservative-free eye drops can help maintain eye moisture. Browse our selection of eye drops for options that complement your treatment plan.
Frequently Asked Questions
Is Tobradex available over the counter in Canada?
No, Tobradex is a prescription medication in Canada. You will need a prescription from your doctor or eye care professional to obtain it.
How long should I use Tobradex?
Tobradex is typically prescribed for 7 to 14 days, but follow your doctor's specific instructions. Do not use it for longer than prescribed, as prolonged steroid use can cause serious side effects.
Can I use Tobradex while wearing contact lenses?
Generally, you should not wear contact lenses while using Tobradex. The preservative benzalkonium chloride in the drops can be absorbed by soft contact lenses. Ask your doctor for specific guidance.
What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Can Tobradex be used for children?
Tobradex can be prescribed for children, but dosage and duration should be determined by a pediatric eye care professional. Children may be more susceptible to steroid side effects.
Final Thoughts
Tobradex is an effective prescription eye drop for treating bacterial eye infections with inflammation. While it provides dual-action relief, it's important to use it exactly as prescribed and be aware of potential side effects, particularly with prolonged use. Always consult your eye care professional for personalized advice about your eye health.
About the Reviewer
Dr. Davinder Sidhu is an optometrist based in British Columbia with a focus on dry eye management and preservative-free solutions. Learn more at TheGenuwineOD.com or follow him on Instagram and Facebook.
